Abstract

Ayurvedic formulations are highly effective and known to have minimal or no side effect, but due to lack of validation parameters for identification and quality control, there is a lacuna in demand of Ayurvedic formulations at international level. Shatsakar Churna is a widely used polyherbal Ayurvedic formulation for constipation and gastric troubles. Standardization and quality control parameters of Shatsakar Churna, are not well defined. The objective of the work is to formulate and standardize the Satsakar Churna according to World Health Organization (WHO), GMP guidelines which are the first available report so far. The formulation was prepared in the Institute’s pharmacy and evaluated for organoleptic characters, powder drug studies, physicochemical parameters (total ash, acid insoluble ash, water soluble ash, water soluble extractive, ethanol soluble extractive), micrometric evaluation (density and flow properties) and phytochemical evaluations. The results of different standardization parameters revealed satisfactory and sufficient data to evaluate the inhouse formulation and can be utilized as reference standards in various quality control aspects of the formulation, powder drug analysis revealed specific identities for crude raw drug which are useful as marker in the preparation and identification of components of the formulation.