Journal article
P. Chakraborty, Y. C. Tripathi, Devesh Tewari, L. Upadhyay, J. Puri
2016
2016
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APA
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Chakraborty, P., Tripathi, Y. C., Tewari, D., Upadhyay, L., & Puri, J. (2016). Phytochemical Evaluation and Antiinflammatory Effects of Hymenodictyon excelsum (Roxb.) Wall Grown in Uttarakhand State of India.
Chicago/Turabian
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Chakraborty, P., Y. C. Tripathi, Devesh Tewari, L. Upadhyay, and J. Puri. “Phytochemical Evaluation and Antiinflammatory Effects of Hymenodictyon Excelsum (Roxb.) Wall Grown in Uttarakhand State of India” (2016).
MLA
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Chakraborty, P., et al. Phytochemical Evaluation and Antiinflammatory Effects of Hymenodictyon Excelsum (Roxb.) Wall Grown in Uttarakhand State of India. 2016.
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@article{p2016a,
title = {Phytochemical Evaluation and Antiinflammatory Effects of Hymenodictyon excelsum (Roxb.) Wall Grown in Uttarakhand State of India},
year = {2016},
author = {Chakraborty, P. and Tripathi, Y. C. and Tewari, Devesh and Upadhyay, L. and Puri, J.}
}
Abstract
Background: A number of medicinal plants have traditionally been used as potent anti-inflammatory drug. The present study was aimed at phytochemical evaluation and assessment of anti-inflammatory activity of bark of Hymenodictyon excelsum (Roxb.) Wall., a deciduous tree in the Himalayan region of India. Methods: Different extracts of the bark were qualitatively evaluated for presence and/or absence of different types of phytochemicals. Physicochemical evaluation and TLC profiling of extracts was carried out to develop standard parameters for authentication. The anti-inflammatory activity of the methanolic extract was carried out by egg albumin induced rat paw edema model. Results: The phytochemical evaluation showed the presence of highest number of secondary metabolites in the methanol extract. The tested plant exhibited significant anti-inflammatory activity comparable to the standard anti-inflammatory drug Piroxicam. Conclusion: The study led to the conclusion that the bark of H. excelsum possesses promising anti-inflammatory efficacy. Results of physicochemic al and phytochemical studies provided the scientific basis to bioefficacy of the plant. However, further research is needed on the active ingredient of the plant responsible for anti-inflammatory and other biological activity.